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Showing posts with label aspirin. Show all posts

Science Confirms Turmeric More Effective than 14 Different Pharmaceutical Drugs


Image: delicioushappens.com
by Sayer Ji | greenmedinfo.com

Turmeric is one the most thoroughly researched plants in existence today.  Its medicinal properties and , and acquired either as a retail item or with 200 GMI-tokens, for those of you who are already are members and receive them automatically each month.
Downloadable Turmeric Document page
components (primarily curcumin) have been the subject of over 5600 peer-reviewed and published biomedical studies.  In fact, our five-year long research project on this sacred plant has revealed over 600 potential preventive and therapeutic applications, as well as 175 distinct beneficial physiological effects. This entire database of 1,585 ncbi-hyperlinked turmeric abstracts can be downloaded as a PDF at our

Related: How to grow turmeric at home

Given the sheer density of research performed on this remarkable spice, it is no wonder that a growing number of studies have concluded that it compares favorably to a variety of conventional medications, including:

Lipitor/Atorvastatin(cholesterol medication): A 2008 study published in the journal Drugs in R & D found that a standardized preparation of curcuminoids from Turmeric compared favorably to the drug atorvastatin (trade name Lipitor) on endothelial dysfunction, the underlying pathology of the blood vessels that drives atherosclerosis, in association with reductions in inflammation and oxidative stress in type 2 diabetic patients. [i]  [For addition curcumin and 'high cholesterol' research – 8 abstracts]

Corticosteroids (steroid medications): A 1999 study published in the journal Phytotherapy Research found that the primary polyphenol in turmeric, the saffron colored pigment known as curcumin, compared favorably to steroids in the management of chronic anterior uveitis, an inflammatory eye disease.[ii]  A 2008 study published in Critical Care Medicine found that curcumin compared favorably to the corticosteroid drug dexamethasone in the animal model as an alternative therapy for protecting lung transplantation-associated injury by down-regulating inflammatory genes.[iii] An earlier 2003 study published in Cancer Letters found the same drug also compared favorably to dexamethasone in a lung ischaemia-repurfusion injury model.[iv]  [for additional curcumin and inflammation research – 52 abstracts]

Prozac/Fluoxetine & Imipramine  (antidepressants): A 2011 study published in the journal Acta Poloniae Pharmaceutica found that curcumin compared favorably to both drugs in reducing depressive behavior in an animal model.[v] [for additional curcumin and depression research – 5 abstracts]
Aspirin (blood thinner): A 1986 in vitro and ex vivo study published in the journal Arzneimittelforschung found that curcumin has anti-platelet and prostacyclin modulating effects compared to aspirin, indicating it may have value in patients prone to vascular thrombosis and requiring anti-arthritis therapy.[vi]  [for additional curcumin and anti-platelet research]

Anti-inflammatory Drugs: A 2004 study published in the journal Oncogene found that curcumin (as well as resveratrol) were effective alternatives to the drugs aspirin, ibuprofen, sulindac, phenylbutazone, naproxen, indomethacin, diclofenac, dexamethasone, celecoxib, and tamoxifen in exerting anti-inflammatory and anti-proliferative activity against tumor cells.[vii] [for additional curcumin and anti-proliferative research – 15 abstracts]

Oxaliplatin (chemotherapy drug): A 2007 study published in the International Journal of Cancer found that curcumin compares favorably with oxaliplatin as an antiproliferative agenet in colorectal cell lines.[viii] [for additional curcumin and colorectal cancer research – 52 abstracts]

Metformin (diabetes drug): A 2009 study published in the journal Biochemitry and Biophysical Research Community explored how curcumin might be valuable in treating diabetes, finding that it activates AMPK (which increases glucose uptake) and suppresses gluconeogenic gene expression  (which suppresses glucose production in the liver) in hepatoma cells. Interestingly, they found curcumin to be 500 times to 100,000 times (in the form known as tetrahydrocurcuminoids(THC)) more potent than metformin in activating AMPK and its downstream target acetyl-CoA carboxylase (ACC). [ix]

Continue reading at greenmedinfo.com

Citations:

[i] P Usharani, A A Mateen, M U R Naidu, Y S N Raju, Naval Chandra. Effect of NCB-02, atorvastatin and placebo on endothelial function, oxidative stress and inflammatory markers in patients with type 2 diabetes mellitus: a randomized, parallel-group, placebo-controlled, 8-week study. Drugs R D. 2008;9(4):243-50. PMID: 18588355
[ii] B Lal, A K Kapoor, O P Asthana, P K Agrawal, R Prasad, P Kumar, R C Srimal. Efficacy of curcumin in the management of chronic anterior uveitis. Phytother Res. 1999 Jun;13(4):318-22. PMID: 10404539
[iii] Jiayuan Sun, Weigang Guo, Yong Ben, Jinjun Jiang, Changjun Tan, Zude Xu, Xiangdong Wang, Chunxue Bai. Preventive effects of curcumin and dexamethasone on lung transplantation-associated lung injury in rats. Crit Care Med. 2008 Apr;36(4):1205-13. PMID: 18379247
[iv] J Sun, D Yang, S Li, Z Xu, X Wang, C Bai. Effects of curcumin or dexamethasone on lung ischaemia-reperfusion injury in rats. Cancer Lett. 2003 Mar 31;192(2):145-9. PMID: 18799504
[v] Jayesh Sanmukhani, Ashish Anovadiya, Chandrabhanu B Tripathi. Evaluation of antidepressant like activity of curcumin and its combination with fluoxetine and imipramine: an acute and chronic study. Acta Pol Pharm. 2011 Sep-Oct;68(5):769-75. PMID: 21928724
[vi] R Srivastava, V Puri, R C Srimal, B N Dhawan. Effect of curcumin on platelet aggregation and vascular prostacyclin synthesis. Arzneimittelforschung. 1986 Apr;36(4):715-7. PMID: 3521617
[vii] Yasunari Takada, Anjana Bhardwaj, Pravin Potdar, Bharat B Aggarwal. Nonsteroidal anti-inflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferation. Oncogene. 2004 Dec 9;23(57):9247-58. PMID: 15489888
[viii] Lynne M Howells, Anita Mitra, Margaret M Manson. Comparison of oxaliplatin- and curcumin-mediated antiproliferative effects in colorectal cell lines. Int J Cancer. 2007 Jul 1;121(1):175-83. PMID: 17330230
[ix] Teayoun Kim, Jessica Davis, Albert J Zhang, Xiaoming He, Suresh T Mathews. Curcumin activates AMPK and suppresses gluconeogenic gene expression in hepatoma cells. Biochem Biophys Res Commun. 2009 Oct 16;388(2):377-82. Epub 2009 Aug 8. PMID: 19665995
[x] GreenMedInfo.com, Curcumin Kills Drug Resistant Cancers, 54 Abstracts
[xi] GreenMedInfo.com, Curcumin Kills Multi-Drug Resistant Cancers: 27 Abstracts.

Tylenol Just Once A Month Raises A Child’s Asthma Risk 540%

by Sarah Couture Pope

The vast majority of babies are given Tylenol (acetaminophen) within the first six months of life. It is the go to medicine for modern parents whenever discomfort or fever strikes even very young children and its use is frequently encouraged by many pediatricians.
Image: goeshealth.com

Now, a major study of over 20,000 children suggests that giving this popular medicine even as infrequently as once per year could have a permanent, life-threatening health effect.

Researchers at the University of A Coruna in Spain asked the parents of 10,371 children ages 6-7 and 10,372 adolescents aged 13-14 whether their children had asthma and how often they had been given acetaminophen within the previous year and when they were babies.
The children in the younger age group who had received the medicine only once per year were at 70% greater risk for asthma while those receiving Tylenol once a month or more were shockingly 540% more likely to have asthma.

The study, published in the European Journal of Public Health, also found that children who had even a single dose of Tylenol before their first birthday had a 60% risk of developing asthma.

In the older age group of 13 and 14 year-olds, asthma was 40 percent more likely if they had taken acetaminophen within the previous 12 months. The young teenagers were 250% more at risk if they took it once a month.

The researchers speculated that Tylenol, called paracetamol in the UK, may reduce a potent antioxidant called glutathione in the lungs and blood, which results in damage to the lung tissue. Glutathione is produced by the body (it is a combination of three amino acids:  cysteine, glycine and glutamine) and is referred to as the “mother” of all antioxidants by Dr. Mark Hyman MD.
While Tylenol use is strongly associated with a significant increase in asthma and the effect is greater the more often the drug is taken, no causal link is yet established via randomized-controlled trials. Does this mean the results of this large study should be dismissed and parents should continue favoring use of the popular over the counter medication for fever and pain?
Not so fast.

It would certainly be the wise and cautious approach for parents to investigate alternatives to Tylenol while additional follow-up research is performed.

Asthma rates have been on the increase for decades at the same time Tylenol use became more widespread. The potential link cannot and should not be ignored.

Examination of 20,000 children establishing such a strong associative risk must be taken seriously and the dismissal of the research by some doctors is irresponsible given the seriousness and life altering outcome of an asthma diagnosis.

“All the asthma symptoms analysed increased significantly with paracetamol consumption,” the researchers wrote.
Sources: RealFarmacy & The Healthy Economist

Article sources:

Babies given Calpol just once a month ‘are five times as likely to develop asthma’

Glutathione: The Mother of All Antioxidants

It’s Too Soon to Blame Paracetemol for Rising Childhood Asthma Rates

Exposure to Paracetemol and Asthma Symptoms

The effects of early and late paracetamol exposure on asthma and atopy: a birth cohort

Prenatal and infant acetaminophen exposure, antioxidant gene polymorphisms, and childhood 

asthma

Acetaminophen use and the risk of asthma in children and adults: a systematic review and 

metaanalysis

Reduce Your Child’s Asthma Risk by 41%

50 Awesome Household Tips

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1) Toothpaste: Buff a CD/DVD
Apply toothpaste to a cotton ball and wipe the disc. Wash with water afterwards and you’ve got a brand new disc!
2) Cornstarch: Untangle Knots
Sprinkling cornstarch into tough knots, such as shoe laces helps loosen them.
3) Walnut: Buff Dings out of Wood Furniture
Get rid of unsightly scratches and dings on wood furniture by rubbing a walnut on the areas. The blemishes will vanish quickly and your furniture and pocket book will be saved.
4) Club Soda: Make Your Breads Fluffier
When baking, where recipes call for water, add club soda instead to make pancakes, waffles and any other breads fluffier.
5) Salt: Keep Windows Frost Free
Pour a cup of salt into a liter of water. Sponge the liquid onto the inside of window to prevent frost from forming during the winter months.
6) Rubbing Alcohol: Remove Permanent Marker
Dab the surface that has the permanent marker on it with a cloth or cotton ball covered in rubbing alcohol to make it disappear quickly.
7) Chap stick: Stops Bleeding When Nicked Shaving
Cut yourself shaving? Just swipe some chap stick over the cut to stop that constant bleeding. No more tissue squares!
8) Apple Juice: Removes Dandruff
Don’t ask how it works, but it does! Instead of buying a special shampoo, just wash your hair in apple juice to rid your scalp of pesky dandruff.
9) Aspirin: Get Rid of Armpit Stains on T-Shirts
Grind up an aspirin tablet or two, then make a paste out of it using water, lemon or vinegar. Spread the paste on the stained area and let sit for an hour before washing.
10) Olive Oil: Make Pets’ Coat Shinier
Add a bit of olive oil to your pet’s food to give them a healthier, shinier coat of fur.
11) Newspapers: Clean Windows and Mirrors
Instead of using a spray and a streaky cloth, use only newspaper to clean off your mirrors and windows for a streak-free finish.
12) Baking Soda: Remove Bugs from Windshield
Mix baking soda with warm water to make a paste. Spread the paste over your windshield for fifteen minutes. Then wipe or spray off with a hose.
13) Bleach: Extend Life of Flowers in Vase
Add a few drops of bleach to vase water to prevent the build-up of the slime caused by bacteria. It works just like chlorine in a swimming pool.
14) Kitchen Dish Soap: Flea-Killing Dog Shampoo
Kitchen dish soap (not dish detergent) can double as dog shampoo for its flea killing abilities.
15) Coke: Remove Blood Stains from Clothing
Soak the stain in coke until the stain is dissolved, then wash the clothing as usual. Wash before the coke dries, though.
16) Honey: Remove Blemish Overnight
Have a blemish you need to get rid of by tomorrow? Put a dab of honey on the blemish and cover it up (it’s best to use a Band-Aid) and the honey’s natural antibacterial properties will clean out the bacteria by the morning.
17) Wax Paper: Clean Can Opener Gears
Run a few small strips of wax paper through the can opener to clean out of the bits and pieces that have built up in the gears throughout the year. The wax will also rub off on the gears to protect for future use as well.
18) WD-40: Remove Crayons from Walls
Use the lubricant and a cloth to remove stubborn crayon marks from the walls just by spraying the wall and wiping with a cloth.
19) Chalk: Keep Ants and Slugs Out of the House
Ants and Slugs Won’t Touch Chalk. So, simply draw a line in front of your doorway where you are having problems with these pesky critters and they won’t cross it, meaning they won’t be able to get into your house.
20) Vinegar: Kills Weeds and Helps Flowers Grow
Vinegar is a magic wonder when it comes to gardening. It not only kills weeds but they help flowers grow as well. Douse vinegar all around your garden to prevent weeds from popping up and to help your flowers to grow healthy and strong.
21) Mayonnaise: Remove Bumper Sticker
Spread mayonnaise on the bumper sticker and let sit for at least thirty minutes. Then, rub the sticker off with a towel, leaving a clean bumper!
22) Tin Foil Ball: Replace Dryer Sheets Permanently
Instead of using a dryer sheet ball up one or a few sheets of tin foil and toss it in the dryer. It removes the static electricity from your clothes and one can last up to a year.
23) Banana Peel: Polish Leather Shoes
Use the inside of a banana peel to give shoes a professional and natural shine that will last for quite some time.
24) Mouthwash: Cure Athlete’s Foot
Pour mouthwash on cotton balls and then swab your feet. The alcohol will disinfect the bacteria completely if you continue this for a week or so.
25) Baking Soda: Clean BBQ Grill
Mix a cup of baking soda with half a cup water to make a paste. Dip your brush into the paste and scrub the grill. The caked on pieces and black residue will come off much quicker and using baking soda is much safer and cheaper than using cleaning chemicals.
26) Coffee Grounds: Fertilizer
Coffee is full of nutrients and vitamins that are very beneficial to soil. That’s why some people include it in compost piles. If you want to get the most out of your coffee, pour the grounds on areas where you want more grass or flowers.
27) Olive Oil: Shaving Cream
The smoothness of the oil can replace the need for shaving cream, and it also provides great moisture.
28) Dryer Sheets: Gets Rid of Static Electricity
Use dryer sheets to remove static electricity from things such as clothing, TV screens or your own hair. Tame fly away strands by running a dryer sheet over them.
29) Freezer: Freeze Candles to Make Them Last Longer
Put candles in the freezer for at least 2 hours before using. Once you burn them, the wax will melt at a much slower pace, making them last much longer!
30) Two glasses of water: Cure Headache
Water is the cure to most common headaches. To make the headache go away quickly, drink two cups of water very quickly.
31) Lemons: Deodorize Garbage Disposal
Toss whole slices of lemon into the garbage disposal then run it. The acidity of the lemon will rid your sink of all odors and leave a fresh scent that usually lasts for a few months.
32) Alka Seltzer: Remove Burnt-On Grease and Food Stains
When letting your pots and pans soak, throw in one or two Alka Seltzer tablets and the caked on residue from cooking will come off easily when you scrub/wash.
33) Apple Cider Vinegar: Relieve Diarrhea
Mix two tablespoons of apple cider vinegar into eight ounces of water to soothe your stomach. The taste may not be the greatest, but the antibacterial properties of the vinegar will end the unpleasantness of the bowel problems.
34) Toothpaste: Remove Scratches from Glass
Apply toothpaste to scratch, then rub with a cloth until the scratch is gone. Make sure the glass is clean beforehand.
35) Cheerios: Relieve Pain from Poison Ivy, Chickenpox and Sunburns
Pound one to four cups of Cheerios into a powder and add to your bath to soothe your skin while you soak. You may not feel relief while in the tub, but you will soon after.
36) Buttons: Sort Earrings
Organize your earrings and prevent them from becoming entangled by using spare buttons as holders for each pair.
37) Corn Oil: Prevent Hairballs for Pets
Add a few drops of corn oil to your pets’ food to prevent hairballs from forming. The thick oil helps the fur pass through the animal’s system much quicker and easily.
38) Whipped Cream: Remove Gum from Hair
There are many remedies for removing gum from hair, but this is a lesser known one. Give it a try rather than peanut butter the next time you’re in need.
39) Coke: Remove Oil Stains from the Driveway
Oil stains are very difficult to remove pavement, but one method guaranteed to work is Coke. The highly acidic drink will eat away at the oil until clean.
40) Brown Sugar: Facial Scrub
A scrub is good to do about once a month to remove dead skin and bacteria built up in pores and remove excess oil from the skin. Brown sugar does just as well as expensive products and will definitely result in a clearer and smoother complexion.
41) Dryer Sheet: Lint Brush
You already know that dryer sheets remove lint in the dryer. Well, it can do the same thing out of the dryer, too. When you’re in a fix, use a dryer sheet. It works just as well as a lint brush, and if you like the scent, it’s an added bonus.
42) Newspaper: Deodorize food containers and Food Drawers in the Refrigerator
For that stinky Tupperware or smelly refrigerator drawer that is too much to deal with, toss in a sheet of newspaper overnight before you deal with it. The paper will absorb the smell greatly reducing it or eliminating it completely.
43) Olive Oil: Un-stick a Zipper
The oil will help the zipper slide more easily, fixing the problem!
44) Salt: Cool Something Quickly
You know that feeling when you’re having a BBQ and someone asks for a drink and you realize that no one has put them in the cooler? There’s nothing worse than a warm drink on a hot day. Chill a drink quickly, by adding salt and water to your ice. The drinks will be cold in a matter of minutes; saving your party and making you look smart all at once.
45) Scotch Tape: Prevent Wall from Chipping When Nailing
The wall can leave unsightly chips when hammering in a nail. Prevent this by simply placing a piece of scotch tape over the area you’re going to nail. The wall will be held tighter, preventing chips from occurring.
46) Alka Seltzer: Soothe Insect Bites
Dissolve two tablets into a glass of water. Then use a cloth or cotton ball to apply it to the affected area. The red will go down and most importantly, the itchiness will vanish usually in fifteen minutes.
47) Lemon: Whitens Whites
Add about half a cup of lemon juice to your load of whites to makes them extra white. You can use lemon juice with bleach or detergent, so don’t worry about mixing chemicals with the acidic lemon.
48) Banana Peel: Whiten Teeth
This may sound a little odd, but rub the inside of a banana peel on your teeth twice a day for two weeks and you will receive the same effect from a teeth-whitening kit. Plus, you’ll save yourself money and the hassle of using chemicals.
49) Hair Dryer: Free Photos Stuck on Pages
If you have a photo stuck on a page that you can’t get free, try using a blow dryer on the back of the page. It will loosen the photo from the page and the adhesive holding it there.
50) Banana Peel: Heal Most Skin Problems
Bananas are the magical fruit, because they heal many common problems on the skin. By rubbing the peel on your skin, you can heal bruises and cuts and eliminate rashes, itching and warts. Basically if you have a common skin problem, it can be cured by this fruit.

Source : Dave Sommers

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